Personal profile
Education
o (1996) M.D., Yonsei University
o (1998) M.S., Yonsei University
o (2001) Ph.D., Yonsei University
o (1998) M.S., Yonsei University
o (2001) Ph.D., Yonsei University
Professional Experience
o (2021~Present) Director, The Center for Viral Immunology, Korea Virus Research Institute, IBS, Daejeon, Korea
o (2007~Present) Assistant Professor, Associate Professor, and Professor, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea
o (2002~2007) Postdoctoral Fellow, National Institutes of Health (NIH), Bethesda, MD, USA
o (2007~Present) Assistant Professor, Associate Professor, and Professor, Graduate School of Medical Science and Engineering, KAIST, Daejeon, Korea
o (2002~2007) Postdoctoral Fellow, National Institutes of Health (NIH), Bethesda, MD, USA
Research interests
Viral Immunology, Viral Hepatitis, COVID-19, Tumor Immunology, Immune Aging, Human Immunology
Major Research Achievements
o Discovery of pathological significance of bystander T cell activation and underlying mechanisms in human viral disease
o Elucidation of characteristics of memory T cells elicited by SARS-CoV-2 infection or vaccination and their role in protective immunity
o Characterization of senescent T cells and their significance in cardiovascular diseases
o Elucidation of mechanisms underlying T cell exhaustion at cellular and molecular levels in human cancer
o Elucidation of characteristics of memory T cells elicited by SARS-CoV-2 infection or vaccination and their role in protective immunity
o Characterization of senescent T cells and their significance in cardiovascular diseases
o Elucidation of mechanisms underlying T cell exhaustion at cellular and molecular levels in human cancer
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Author Correction: A virtual memory CD8+ T cell-originated subset causes alopecia areata through innate-like cytotoxicity (Nature Immunology, (2023), 24, 8, (1308-1317), 10.1038/s41590-023-01547-5)
Seok, J., Cho, S. D., Lee, J., Choi, Y., Kim, S. Y., Lee, S. M., Kim, S. H., Jeong, S., Jeon, M., Lee, H., Kim, A. R., Choi, B., Ha, S. J., Jung, I., Yoon, K. J., Park, J. E., Kim, J. H., Kim, B. J., Shin, E. C. & Park, S. H., Jan 2026, In: Nature Immunology. 27, 1, p. 166 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Robust effector memory features of human T-bethi B cells induced by repeated mRNA vaccination
Lee, J., Son, S., Chung, Y., Cho, S. D., Kwon, J. S., Bae, S., Seok, J., Choi, B., Jung, I., Oh, J. E., Shin, E. C., Kim, S. H. & Park, S. H., 20 Feb 2026, In: iScience. 29, 2, 114804.Research output: Contribution to journal › Article › peer-review
Open Access -
Co-blockade of TGFβ and PD-1 Reinvigorates Glioblastoma-Infiltrating CD8+ T Cells That Characteristically Upregulate TGFβRI Expression
Kim, A. R., Jeon, S. H., Park, J., Kim, E. S., Kwon, M., Yoo, J., Kang, S. G., Park, S. H., Chang, J. H. & Shin, E. C., 1 Aug 2025, In: Clinical Cancer Research. 31, 15, p. 3306-3316 11 p.Research output: Contribution to journal › Article › peer-review
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Detecting signatures of surface antibonding nodes through atomic-scale thermopower
Baek, S., Shin, E. C., Seo, J. & Kim, Y. H., 15 Mar 2025, In: Applied Surface Science. 685, 162027.Research output: Contribution to journal › Article › peer-review
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GX-I7, a long-acting IL-7, safely and effectively increased peripheral CD8+/CD4+ T cells and TILs in patients with locally advanced or metastatic solid tumours
Kim, G. M., Kim, S., Lee, M. A., Byun, M. S., Choi, D., Yang, S. H., Woo, J. W., Sung, Y. C., Shin, E. C., Park, S. H., Kim, T. W. & Sohn, J., 7 Sep 2025, In: British Journal of Cancer. 133, 4, p. 524-532 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations