Calculated based on number of publications stored in Pure and citations from Scopus
20022025

Research activity per year

Personal profile

Education

o (1995) B.E., Dongguk University
o (1998) M.S., Yonsei University
o (2009) Ph.D., Yale University

Professional Experience

o (2022~Present) Professor, KAIST, Daejeon, Korea
o (2016~2022) Associate Professor, KAIST, Daejeon
o (2009~2016) Assistant Professor, KAIST, Daejeon
o (2009~2009) Postdoctoral Associate, Yale University, New Haven, CT, USA

Research interests

Brain cancer, gd T cells, Tumor microenvironment, HSV infection, Gut microbiota, Immune regulation

Major Research Achievements

o Identification of tumor hypoxia which represses γδ T cell-mediated antitumor immunity against brain tumors.
o Identification of supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation. 
o Identification of the regulation of c-SMAC formation and AKT-mTOR signaling by the TSG101-IFT20 axis in CD4+ T cells 
o Identification of Obesity which enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells.
o Identification of blood monocyte-derived CD169+ macrophages which contribute to antitumor immunity against glioblastoma.
o Development of intranasal delivery of an adenovirus-vector vaccine co-expressing a modified spike protein and a genetic adjuvant confers lasting mucosal immunity against SARS-CoV-2.
o Identification of factors which determines the severity of COVID-19 by the analysis of single cell transcriptome 
o Identification of Autophagic protein ATG5 which controls anti-viral immunity via glycolytic reprogramming of dendritic cells against respiratory syncytial virus infection. 
o Development of multivalent DNA vaccine which protects against genital herpes by T-cell immune induction in vaginal mucosa. 
o Identification of Autophagy protein ATG5 which regulates CD36 expression and anti-tumor MHC class II antigen presentation in dendritic cells. 
o Identification of a mechanism for the induction of type 2 immune responses by a protease allergen in the genital tract.
o Identification of the role of dysbiosis-induced IL-33 which contributes to impaired antiviral immunity in the genital mucosa.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Related documents

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