Research output per year
Research output per year
Personal profile
Education
o (1999) B.S., KAIST
o (2001) M.S., KAIST
o (2005) Ph.D., KAIST
o (2001) M.S., KAIST
o (2005) Ph.D., KAIST
Professional Experience
o (2011~Present) Assistant Professor, Associate Professor, Professor, KAIST, Daejeon, Korea
o (2018~Present) Chief Investigator, Institute for Basic Science, Daejeon, Korea
o (2023~2023) Visiting Scholar, Institute for Protein Design, University of Washington Seattle, USA
o (2020~2022) Visiting Professor, World Research Hub Initiative (WRHI), Tokyo Institute of Technology, Japan
o (2007~2011) Postdoctoral Researcher, University of California, San Francisco, USA
o (2006~2007) Postdoctoral Researcher, KAIST, Daejeon, Korea
o (2018~Present) Chief Investigator, Institute for Basic Science, Daejeon, Korea
o (2023~2023) Visiting Scholar, Institute for Protein Design, University of Washington Seattle, USA
o (2020~2022) Visiting Professor, World Research Hub Initiative (WRHI), Tokyo Institute of Technology, Japan
o (2007~2011) Postdoctoral Researcher, University of California, San Francisco, USA
o (2006~2007) Postdoctoral Researcher, KAIST, Daejeon, Korea
Research interests
Protein Structure, AI-based Protein Design, Drug Development, Cryo-EM, X-ray Crystallography, Inter-cellular communication, Protein-protein interaction, Ligand-Receptor interaction, Antibody development
Major Research Achievements
o Structure and Mechanism Study on Toll-Like Receptor
o Structure and Mechanism Study on Synaptic Adhesion Protein
o Structure and Mechanism Study on Growth Factor and Cytokine
o Structure and Mechanism Study on Membrane Protein (ion-channel, receptor)
o Therapeutic Antibody development for inducing angiogenesis
o Therapeutics development for the treatment of cancer and/or Age-related macular degeneration
o Protein design of immune-modulator
o Structure and Mechanism Study on Synaptic Adhesion Protein
o Structure and Mechanism Study on Growth Factor and Cytokine
o Structure and Mechanism Study on Membrane Protein (ion-channel, receptor)
o Therapeutic Antibody development for inducing angiogenesis
o Therapeutics development for the treatment of cancer and/or Age-related macular degeneration
o Protein design of immune-modulator
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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ATF5-Dependent GDF15 Expression Mediates Anesthesia-Induced Neuroprotection Against Stroke
Ju, X., Zhang, T., Cui, J., Lee, Y., Lee, S., Kim, H. M., Hong, B., Park, J., Choi, C. H., Yi, H. S., Heo, J. Y. & Chung, W., 14 Jan 2026, In: Advanced Science. 13, 3, e17086.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Atomically accurate de novo design of antibodies with RFdiffusion
Bennett, N. R., Watson, J. L., Ragotte, R. J., Borst, A. J., See, D. L., Weidle, C., Biswas, R., Yu, Y., Shrock, E. L., Ault, R., Leung, P. J. Y., Huang, B., Goreshnik, I., Tam, J., Carr, K. D., Singer, B., Criswell, C., Wicky, B. I. M., Vafeados, D. & Garcia Sanchez, M. & 12 others, , 1 Jan 2026, In: Nature. 649, 8095, p. 183-193 11 p.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
Autism-associated ARHGEF9 variants impair GABAergic synapses and ultrasonic communication by reducing gephyrin phosphorylation
Jung, H., Kim, B., Jang, G., Lee, H., Kim, Y., Kim, H., Lee, H. J., Kim, D., Yang, Y., Jeong, W. C., Kim, S., Han, A. R., Kim, H. M., Papadopoulos, T., Durand, B., Francannet, C., Piton, A., Kim, J. Y., Ko, J. & Um, J. W., Mar 2026, In: Molecular Psychiatry. 31, 3, p. 1757-1773 17 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Bazedoxifene reverses sexually dimorphic autistic-like abnormalities in biallelic MDGA1-mutant mice
Kim, S., Kim, H., Pelayo, J. P., Alvarez, S., Jang, G., Kim, J., Kim, B., Hoelscher, V. M., Calleja-Pérez, B., Jung, H., Yang, Y., Lee, H. J., Lee, J., Kim, S., de la Peña, M. J., Lee, Y., Kim, S., Han, A. R., Lee, D. S. & Ji, S. & 9 others, , 15 Apr 2026, In: EMBO Molecular Medicine. 18, 4, p. 1358-1398 41 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Computational Design and Glycoengineering of Interferon-Lambda for Nasal Prophylaxis Against Respiratory Viruses
Yun, J., Yang, S., Kwon, J. H., Vecchietti, L. F., Choi, J. H., Choi, M. R., Ku, K. B., Ro, H. J., Kim, K. D., Cha, M., Chung, H. J., Oh, J. E. & Kim, H. M., 30 Jan 2026, In: Advanced Science. 13, 6, e06764.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Researchers at Korea Advanced Institute of Science and Technology (KAIST) Have Reported New Data on Machine Learning (Research Paper an Application of Machine Learning for Geometric Optimization of a Dual-throat Bent Nozzle)
Hong, J. W., Kim, H. M. & Lee, H.-S.
8/04/25
1 item of Media coverage
Press/Media
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Researchers from School of Electrical Engineering Detail Findings in Telecommunication (Anomaly Detection-Based UE-Centric Inter-Cell Interference Suppression)
19/03/25
1 item of Media coverage
Press/Media
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Korea Advanced Institute of Science and Technology (KAIST) Reports Findings in Nanopatterns (Surface Energy Tailored Reduced Graphene Oxide Top-Coat for Vertical Alignment of High-ch Block Copolymers for Sub-10-nm Nanopatterning)
Kim, S. O., Kim, H. M. & Lee, W.
26/02/25
1 item of Media coverage
Press/Media
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Method for Encoding/Decoding Block Information Using Quad Tree, and Device for Using Same
Kim, Y.-H., Kim, H. M., Kim, Y. & Kim, Y. H.
11/02/25
1 item of Media coverage
Press/Media